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12月26日学术报告

来源： 发布时间：2016-12-22【字体：大 中 小】

　　题目：Probing Tumor Microenvironment with Nonlinear Optical Microscopy 

　　姓名：刘子铭

　　单位：澳门大学

　　时间：2016年12月26日（周一） 下午13:00

　　地点：溢智厅

Abstract
The pathophysiology of tumor is a multicellular and multi-molecular dynamics, with which a network of tumor cells, stromal cells, and immune cells are involved. Although many studies have analyzed hallmark molecules and cells in tumor, most of their evidence were static. They seldom characterize the heterogeneous cellular environment dynamically. Right now, novel multiphoton microscopy can time-course record 3D dynamics of tumor microenvironment at a single-cell resolution. It provides an opportunity to investigate the collagen remodeling, angiogenesis, and cell-cell interaction in the tumor microenvironment. Combined with novel molecular probes, physiological condition like vessel permeability, oxygen concentration, and treatment responses can be investigated in vivo. The results can provide interesting and insightful information for the design of targeting therapy or screening of drugs.

Biography
Tzu-Ming Liu received the B.S. degree in Electrical Engineering from National Taiwan University in 1999 and the Ph.D. degrees in Photonics & Optoelectronics from National Taiwan University in 2004. After the postdoctoral research in the same institute (2005-2009), he became an assistant professor at the Institute of Biomedical Engineering, National Taiwan University since 2009 and was promoted to associate professor in 2013. Since 2016, he was with the Faculty of Health Sciences, University of Macau. His research interests were primarily concerned with ultrafast optics, nanophotonics, tumor biology, the pharmacokinetics of nanomedicines and medical spectroscopy. He developed a series of courses for medical device innovation and started to develop medical devices. He led a student team to won the Outstanding Startup Award in 2014 and co-founded a medical device company, FlatMedical Inc. in 2015.

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                                                               2016-12-22

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